Gys picked up women before they ever heard the term neg. I do think a motion picture featured as cinemas would alter the game as we play it now, though.
Books, magazines, and periodicals go in one eye and out the other. Unless you catch her right after she finished reading an article with a particular or very similar opener or neg, I bet she still won't catch it. Whats more likely is that your wing will try to open the same girl as you, and if both of you used opinion openers then they will respond, "We already had that one used on us" or something similar.
My thoughts and baseless predictions:
Too many guys sarging with the same style in one nightclub is bad. The same girls get opened with the same crap, and although this still tends to work, it just is less than ideal. You may have to occasionally suffer a minor shyt test, especially if it is a moving set. Better yet come up with something more unique. Be original. Have a
soul!
Canned, popular Opinion openers are basically a pickup line nowdays. They have a limited shelf life, and will have to be replaced with new ones once the movie hits (assuming it does).
Most guys will never do much of anything. 99% of all new guys will never finish the newbie mission. Alot will run around for a month or two spitting out random lines and hanging with their buds, most will reach full close about once a month or even less for the really AFC ones!!! They are really not going to create much of a problem.
Shyt tests won't work as well for girls now. They will get busted more frequently. The cat is out of the bag, and women lose a very valuable weapon against men.
The truth is getting out there. Men are going to fight child support and maintennance more now that they see the true nature of what has been going on. The Nice guys will try to become bad boys and most will look ridiculas and be jokes.
This stuff will slowly seep into dating advice colunms and advice books, but it is going to take some time for thatto go full circle.
Marriage is a doomed instution. LOL. Nice guys will try even harder to get married to avoid the competetion. PUAS will bang the wives and get them to leave with all the NICE GUYS $$$$. So divorce attorneys will get richer, faster. Mail order brides will become a huge bussiness. And we will thank the nice guys for putting new, beautiful women into our countries for us to fvck for them.
Mystery will be the richest mutha fucka that ever lived and bill gates will seek his financial advice

Throw you cup up to the PUAs. This is going to be great! I'm already having a blast and we are just getting started.